High-throughput characterization of mutations in antioxidant responsive elements

Understanding the binding specificity of transcription factors is an important step towards accurate computational prediction of regulatory sequences governing gene expression. Higher-throughput binding site characterization methods have long been available in the laboratory for the study of protein...

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Bibliographic Details
Main Author: Chou, Alice
Language:English
Published: University of British Columbia 2008
Subjects:
DNA
Online Access:http://hdl.handle.net/2429/1710