Structural studies of gelsolin and binding partners
Gelsolin is composed of six similarly folded domains, G1 through G6. It controls actin dynamics through its calcium-sensitive ability to bind to, sever, and cap F-actin filaments. This project was designed to test and extend current models for gelsolin activity by growing crystals of intact gelsolin...
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| Language: | English |
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University of British Columbia
2012
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| Online Access: | http://hdl.handle.net/2429/42921 |