Cdh11 Acts as a Tumor Suppressor in a Murine Retinoblastoma Model by Facilitating Tumor Cell Death

Cdh11 Acts as a Tumor Suppressor in a Murine Retinoblastoma Model by Facilitating Tumor Cell Death

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Retinoblastoma, a rare childhood cancer of the retina, is characterized by loss of both alleles of the RB1 gene. However, additional mutational events are required for malignancy. CGH studies described common chromosomal changes indicating potential oncogenes and tumor suppressor genes. Previous wor...

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Bibliographic Details
Main Author: Yurkowski, Christine
Other Authors: Gallie, Brenda L.
Language:en_ca
Published: 2010
Subjects:
Retinoblastoma
Cdh11
Apoptosis
0307
0369
0992
Online Access:http://hdl.handle.net/1807/24658

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