Characterizing the Role of Regulator of G-protein Signalling 4 as a Mediator of Sinoatrial Node and Atrial Cardiomyocyte Function
Heart rate is modulated by the opposing activities of sympathetic and parasympathetic inputs to pacemaker cardiomyocytes in the sinoatrial (SA) node. Parasympathetic activity on nodal myocytes is mediated by acetylcholine-dependent stimulation of M2 muscarinic receptors and activation of Gαi/o sign...
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| Language: | en_ca |
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2010
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| Online Access: | http://hdl.handle.net/1807/26139 |