The Effects of CREB-mediated BDNF Expression on Memory- and Anxiety-related Behaviours in the Adult Mouse

The Effects of CREB-mediated BDNF Expression on Memory- and Anxiety-related Behaviours in the Adult Mouse

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Experience drives changes in gene expression that mold and reorganize neuronal circuits. In response to neuronal activity, the transcription factor CREB binds to a regulatory site on Bdnf promoter IV to modulate BDNF protein levels. CREB and BDNF are extensively implicated in animal behaviour, but t...

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Bibliographic Details
Main Author:	Florczynski, Matthew
Other Authors:	Josselyn, Sheena
Language:	en_ca
Published:	2012
Subjects:	transgenic mice memory anxiety motor learning fear conditioning water maze CREB BDNF behaviour activity-dependent 0317
Online Access:	http://hdl.handle.net/1807/33420

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