WNT signalling in kidney development and autosomal dominant polycystic kidney disease

During kidney development, there is a switch from predominantly canonical to non-canonical WNT signalling. This switch transitions the developing kidney from a state of active proliferation to that of terminal differentiation. The current belief is that a defect in this switch is an underlying mec...

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Bibliographic Details
Main Author: Miller, Michelle
Other Authors: Paul Rowland Goodyer (Supervisor)
Format: Others
Language:en
Published: McGill University 2011
Subjects:
Online Access:http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=103736

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