The effects of anoxia and lack of substrate on the subsequent carbohydrate metabolism of brain tissue.

The effects of anoxia and lack of substrate on the subsequent carbohydrate metabolism of brain tissue.

This series of experiments is based on work done by Dickens and Greville (1933) and Elliott am Henry (1946, 2). Dickens and Greville found that depriving brain slices of both substrate and oxygen for even short periods of time at 38° caused a marked decrease in the anaerobic glycolytic activity of t...

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Bibliographic Details
Main Author: Cross, Jean. D.
Other Authors: Elliott, K. (Supervisor)
Format: Others
Language:en
Published: McGill University 1955
Subjects:
Biochemistry.
Online Access:http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=109934
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spelling ndltd-LACETR-oai-collectionscanada.gc.ca-QMM.1099342014-02-13T03:49:25ZThe effects of anoxia and lack of substrate on the subsequent carbohydrate metabolism of brain tissue.Cross, Jean. D.Biochemistry.This series of experiments is based on work done by Dickens and Greville (1933) and Elliott am Henry (1946, 2). Dickens and Greville found that depriving brain slices of both substrate and oxygen for even short periods of time at 38° caused a marked decrease in the anaerobic glycolytic activity of the slices. Three minutes of the pretreatment caused a reduction of the glycolytic activity to 37%, while twenty minutes decreased it to 11-12%. Respiration, in the meanwhile, was only inhibited to about 50% even after forty minutes of anoxia in the absence of substrate at 38°.McGill UniversityElliott, K. (Supervisor)1955Electronic Thesis or Dissertationapplication/pdfenalephsysno: NNNNNNNNNTheses scanned by McGill Library.All items in eScholarship@McGill are protected by copyright with all rights reserved unless otherwise indicated.Master of Science. (Department of Chemistry.) http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=109934
collection NDLTD
language en
format Others
sources NDLTD
topic Biochemistry.
spellingShingle Biochemistry.
Cross, Jean. D.
The effects of anoxia and lack of substrate on the subsequent carbohydrate metabolism of brain tissue.
description This series of experiments is based on work done by Dickens and Greville (1933) and Elliott am Henry (1946, 2). Dickens and Greville found that depriving brain slices of both substrate and oxygen for even short periods of time at 38° caused a marked decrease in the anaerobic glycolytic activity of the slices. Three minutes of the pretreatment caused a reduction of the glycolytic activity to 37%, while twenty minutes decreased it to 11-12%. Respiration, in the meanwhile, was only inhibited to about 50% even after forty minutes of anoxia in the absence of substrate at 38°.
author2 Elliott, K. (Supervisor)
author_facet Elliott, K. (Supervisor)
Cross, Jean. D.
author Cross, Jean. D.
author_sort Cross, Jean. D.
title The effects of anoxia and lack of substrate on the subsequent carbohydrate metabolism of brain tissue.
title_short The effects of anoxia and lack of substrate on the subsequent carbohydrate metabolism of brain tissue.
title_full The effects of anoxia and lack of substrate on the subsequent carbohydrate metabolism of brain tissue.
title_fullStr The effects of anoxia and lack of substrate on the subsequent carbohydrate metabolism of brain tissue.
title_full_unstemmed The effects of anoxia and lack of substrate on the subsequent carbohydrate metabolism of brain tissue.
title_sort effects of anoxia and lack of substrate on the subsequent carbohydrate metabolism of brain tissue.
publisher McGill University
publishDate 1955
url http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=109934
work_keys_str_mv AT crossjeand theeffectsofanoxiaandlackofsubstrateonthesubsequentcarbohydratemetabolismofbraintissue
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