Effects of a functional oil rich in medium chain triglycerides and phytosterols on plasma lipid profiles and body composition in hypercholesterolemic, overweight men

• Main Author: Roynette, Catherine E.
• Format: Others
• Language: en
• Published: McGill University 2005
• Subjects: Hypercholesteremia > Diet therapy.; Functional foods.; Triglycerides > Health aspects.; Sterols > Physiological effect.; Blood lipids.; Overweight men.; Phytosterols.
• Online Access: http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=84069

Localised accumulation of body fat significantly influences the development of obesity related co-morbidities and cardiovascular disease (CVD) risk. Medium chain triglycerides (MCT) have been suggested to modulate body fat distribution. Phytosterols (PS) have demonstrated unequivocal cholesterol-lowering effects. A healthy dietary solution combining MCT and PS could thus become first-line obesity and CVD prevention. The aim of this study was therefore to investigate the effects of a functional oil (FctO) rich in MCT and PS on blood lipid levels and body adiposity, compared to olive oil. Twenty-three hypercholesterolemic, overweight men, were randomly assigned, in a single-blind crossover study, to consume a FctO, or olive oil, incorporated into a 40% fat diet for 6 wks. Blood lipid levels were measured and body composition was assessed. Total and LDL cholesterol were significantly reduced in subjects consuming the FctO versus the control oil. No significant differences for weight or adiposity loss of subjects were observed between the two oils. Results support the cardio-protective role of this FctO.