The role of energy metabolism in the pathogenesis of Alzheimer's disease
In Alzheimer's disease, neuronal degeneration due to apoptosis has been linked to overexpression and aberrant amyloidogenic processing of the amyloid precursor protein (APP), as well as to bioenergetic defects characterized by deficits in the electron transport chain's cytochrome c oxidase...
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| Language: | en_US |
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2007
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| Online Access: | http://hdl.handle.net/1993/1811 |