Antiestrogens modulate the perforin/granzyme pathway of natural killer cell-mediated cytolysis

Antiestrogenic drugs tamoxifen (TX) and toremifene (TO) are known to augment immune cytolysis in tumor targets induced by various killer cells. Here, we show that antiestrogens are capable of enhancing natural killer (NK) cell-mediated cytotoxicity against K562 erythroleukemia cell line and that bot...

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Bibliographic Details
Main Author: Haeryfar, Seyed Mohammad Mansour
Language:en_US
Published: 2007
Online Access:http://hdl.handle.net/1993/1833