Proviral HIV-1 hypermutation: the correlation of APOBEC3G/F and HIV-1 Vif in HIV-1 disease progression

APOBEC3 proteins, in particular APOBEC3G/F, are important innate host factors that contribute to protection from HIV-1 infection by inducing high levels of guanine to adenine nucleotide substitutions (termed hypermutation) during HIV-1 viral replication. These nucleotide substitutions occur at diffe...

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Bibliographic Details
Main Author: De, Sujata Monika
Other Authors: Plummer,Frank (Medical Microbiology and Infectious Diseases) Ball, Blake (Medical Microbiology and Infectious Diseases)
Language:en_US
Published: 2011
Subjects:
Online Access:http://hdl.handle.net/1993/4523