Regulation of the Arf tumor suppressor by E2F transcription factors

Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Biology, 2007. === Vita. === Includes bibliographical references. === Effective tumor suppression requires the appropriate function of two major signaling pathways, the pRB-E2F growth-control pathway and the p53 stress-response pathway...

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Bibliographic Details
Main Author: Iaquinta, Phillip John
Other Authors: Jacqueline A. Lees.
Format: Others
Language:English
Published: Massachusetts Institute of Technology 2008
Subjects:
Online Access:http://hdl.handle.net/1721.1/40955