Fabrication of drug delivery MEMS devices

• Main Author: Lei, Wang S
• Other Authors: Michael J. Cima.
• Format: Others
• Language: English
• Published: Massachusetts Institute of Technology 2010
• Subjects: Materials Science and Engineering.
• Online Access: http://hdl.handle.net/1721.1/58271

Thesis (S.B.)--Massachusetts Institute of Technology, Dept. of Materials Science and Engineering, 2007. === "May 2007." Cataloged from PDF version of thesis. === Includes bibliographical references (p. 19). === There is considerable amount of interest in the immediate treatment of personnel involved in high risk situations on the battlefield. A novel approach to drug delivery on the battlefield based on MEMS technology is discussed. By combining three separately fabricated layers, a single implantable drug delivery device capable of delivering up to 100 mm3 of a vasopressin solution was developed. In vitro release of vasopressin was observed and the I-V response of the bubble generator was characterized. Results show that the voltage at the time of release is ~11V while the current is ~0.35A, giving a power output of 3.79W. The time to total release of the drug was less than 2 minutes. === by Wang Lei. === S.B.