The influence of cyclic pressure and angiotensin II on the biomechanical properties of aortic heart valves

<p>Hypertension, a risk factor for aortic valve stenosis, increases transvalvular load and can elicit extracellular matrix (ECM) remodeling. Elevated cyclic pressure and the vasoactive agent angiotensin II (Ang II) both promote collagen synthesis, an early hallmark of aortic sclerosis. It was...

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Bibliographic Details
Main Author: Myles, Valtresa
Other Authors: James N. Warnock
Format: Others
Language:en
Published: MSSTATE 2013
Subjects:
Online Access:http://sun.library.msstate.edu/ETD-db/theses/available/etd-12192012-143252/