Biaryl ether and biaryl analogs as cannabinoid receptor ligands
Two cannabinoid receptors (CB1 and CB2) belonging to the superfamily of G-protein coupled receptors (GPCRs) play a vital role in multiple physiological functions. CB1 is found primarily in the central nervous system (CNS) and CB2 in the periphery. Those compounds that bind to these receptors, irresp...
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Online Access: | http://hdl.handle.net/2047/d20001155 |
Summary: | Two cannabinoid receptors (CB1 and CB2) belonging to the superfamily of G-protein coupled receptors (GPCRs) play a vital role in multiple physiological functions. CB1 is found primarily in the central nervous system (CNS) and CB2 in the periphery. Those compounds that bind to these receptors, irrespective of their structure, are considered cannabinoids. It is because of the widespread receptor distribution and its potential therapeutics that this is an attractive receptor
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