Specificity of damage-bypass DNA polymerases E. coli DinB and human pol κ

DNA damage is a constant threat and can block replication. Y-family DNA polymerases can replicate damaged DNA through the process of translesion synthesis (TLS). Y-family DNA polymerases are conserved in all domains of life and bypass specific DNA damage in either an error-free or error-prone manner...

Full description

Bibliographic Details
Published:
Online Access:http://hdl.handle.net/2047/D20260514