A Biomechanical Analysis of Ape and Human Thoracic Vertebrae Using Quantitative Computed Tomography Based Finite Element Models
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Case Western Reserve University School of Graduate Studies / OhioLINK
2009
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| Online Access: | http://rave.ohiolink.edu/etdc/view?acc_num=case1260218025 |
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ndltd-OhioLink-oai-etd.ohiolink.edu-case12602180252021-08-03T05:33:33Z A Biomechanical Analysis of Ape and Human Thoracic Vertebrae Using Quantitative Computed Tomography Based Finite Element Models Loomis, David Arthur Mechanical Engineering Vertebrae Finite Element Thoracic Ape Human Spontaneous vertebral fractures are common among humans, but not observed in apes. Differences in bone structure associated with increased fracture susceptibility among humans remain unclear. Our aim was to determine how vertebral bone compressive strength varies among apes and humans, and how bone loss affects differences in vertebral strength. QCT-based voxel finite element models derived from quantitative computed tomography (QCT) images of the thoracic vertebrae (T8) were created for apes and humans. Human vertebrae showed significantly reduced bone strength relative to apes with similar body mass (p<0.01) and bone mineral content (p<0.01). Bone loss simulations showed no significant differences in the effect of bone loss on strength among species. Our study suggests human vertebrae are weaker than ape vertebrae after accounting for bone mass, but are not more sensitive to age-related bone loss. Our results support the idea weaker vertebral bone contributes to the unique susceptibility of humans to vertebral fractures. 2009 English text Case Western Reserve University School of Graduate Studies / OhioLINK http://rave.ohiolink.edu/etdc/view?acc_num=case1260218025 http://rave.ohiolink.edu/etdc/view?acc_num=case1260218025 unrestricted This thesis or dissertation is protected by copyright: all rights reserved. It may not be copied or redistributed beyond the terms of applicable copyright laws. |
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NDLTD |
| language |
English |
| sources |
NDLTD |
| topic |
Mechanical Engineering Vertebrae Finite Element Thoracic Ape Human |
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Mechanical Engineering Vertebrae Finite Element Thoracic Ape Human Loomis, David Arthur A Biomechanical Analysis of Ape and Human Thoracic Vertebrae Using Quantitative Computed Tomography Based Finite Element Models |
| author |
Loomis, David Arthur |
| author_facet |
Loomis, David Arthur |
| author_sort |
Loomis, David Arthur |
| title |
A Biomechanical Analysis of Ape and Human Thoracic Vertebrae Using Quantitative Computed Tomography Based Finite Element Models |
| title_short |
A Biomechanical Analysis of Ape and Human Thoracic Vertebrae Using Quantitative Computed Tomography Based Finite Element Models |
| title_full |
A Biomechanical Analysis of Ape and Human Thoracic Vertebrae Using Quantitative Computed Tomography Based Finite Element Models |
| title_fullStr |
A Biomechanical Analysis of Ape and Human Thoracic Vertebrae Using Quantitative Computed Tomography Based Finite Element Models |
| title_full_unstemmed |
A Biomechanical Analysis of Ape and Human Thoracic Vertebrae Using Quantitative Computed Tomography Based Finite Element Models |
| title_sort |
biomechanical analysis of ape and human thoracic vertebrae using quantitative computed tomography based finite element models |
| publisher |
Case Western Reserve University School of Graduate Studies / OhioLINK |
| publishDate |
2009 |
| url |
http://rave.ohiolink.edu/etdc/view?acc_num=case1260218025 |
| work_keys_str_mv |
AT loomisdavidarthur abiomechanicalanalysisofapeandhumanthoracicvertebraeusingquantitativecomputedtomographybasedfiniteelementmodels AT loomisdavidarthur biomechanicalanalysisofapeandhumanthoracicvertebraeusingquantitativecomputedtomographybasedfiniteelementmodels |
| _version_ |
1719421692459089920 |