PEDIGREE QUERY, VISUALIZATION, AND GENETIC CALCULATIONS TOOL

PEDIGREE QUERY, VISUALIZATION, AND GENETIC CALCULATIONS TOOL

Bibliographic Details
Main Author: Kurtcephe, Murat
Language:English
Published: Case Western Reserve University School of Graduate Studies / OhioLINK 2012
Subjects:
Computer Science
pedigree
pedigree query
graphical query interface
graph query
Online Access:http://rave.ohiolink.edu/etdc/view?acc_num=case1339099818
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spelling ndltd-OhioLink-oai-etd.ohiolink.edu-case13390998182021-08-03T05:34:26Z PEDIGREE QUERY, VISUALIZATION, AND GENETIC CALCULATIONS TOOL Kurtcephe, Murat Computer Science pedigree pedigree query graphical query interface graph query Family trees, a.k.a. pedigrees, are becoming increasingly important in human genetics, as pedigrees can be utilized to trace a genetic disorder or trait and to calculate disease risks. In this study, we present a new system for pedigree query, visualization, and genetic calculations. A novel query interface is proposed where users can form complicated queries via an easy-to-use graphical user interface with no need for any knowledge of high level query language such as SQL or XPath. A graph encoding method called NodeCodes enables our system to efficiently evaluate relationship-based queries without traversing the graph or using recursive query calls. The visualization of the pedigree data as a dynamic drawing enables the analysis of query results in a more understandable form. The system also provides genetic calculations including inbreeding, kinship, and identity coefficients. Proposed system performs these calculations by using path-based formulas coupling with NodeCodes to achieve efficiency and scalability. 2012-08-27 English text Case Western Reserve University School of Graduate Studies / OhioLINK http://rave.ohiolink.edu/etdc/view?acc_num=case1339099818 http://rave.ohiolink.edu/etdc/view?acc_num=case1339099818 unrestricted This thesis or dissertation is protected by copyright: all rights reserved. It may not be copied or redistributed beyond the terms of applicable copyright laws.
collection NDLTD
language English
sources NDLTD
topic Computer Science
pedigree
pedigree query
graphical query interface
graph query
spellingShingle Computer Science
pedigree
pedigree query
graphical query interface
graph query
Kurtcephe, Murat
PEDIGREE QUERY, VISUALIZATION, AND GENETIC CALCULATIONS TOOL
author Kurtcephe, Murat
author_facet Kurtcephe, Murat
author_sort Kurtcephe, Murat
title PEDIGREE QUERY, VISUALIZATION, AND GENETIC CALCULATIONS TOOL
title_short PEDIGREE QUERY, VISUALIZATION, AND GENETIC CALCULATIONS TOOL
title_full PEDIGREE QUERY, VISUALIZATION, AND GENETIC CALCULATIONS TOOL
title_fullStr PEDIGREE QUERY, VISUALIZATION, AND GENETIC CALCULATIONS TOOL
title_full_unstemmed PEDIGREE QUERY, VISUALIZATION, AND GENETIC CALCULATIONS TOOL
title_sort pedigree query, visualization, and genetic calculations tool
publisher Case Western Reserve University School of Graduate Studies / OhioLINK
publishDate 2012
url http://rave.ohiolink.edu/etdc/view?acc_num=case1339099818
work_keys_str_mv AT kurtcephemurat pedigreequeryvisualizationandgeneticcalculationstool
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