Technology and Commercial Assessment of a Tissue Regenerating Drug in the Regenerative Medicine Market
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ndltd-OhioLink-oai-etd.ohiolink.edu-case14022499852021-08-03T06:25:18Z Technology and Commercial Assessment of a Tissue Regenerating Drug in the Regenerative Medicine Market Webber, Nicholas R. Biology Bone Marrow Transplant STEP Liver Resection Ulcerative Colitis PGDH PGDH-15 Prostaglandins Stem Cells Regenerative Medicine Sanford "Sandy" Markowitz, MD, PhD, the Markowitz-Ingalls Professor of Cancer at the Case Western Reserve (CWRU) School of Medicine and practicing physician at University Hospitals of Cleveland (UH), is currently developing a first-in-class tissue-regenerating drug (TRD). TRD has the potential to benefit patients across a number of indications including liver surgery, bone marrow transplants, and ulcerative colitis attacks. TRD inhibits 15-prostaglandin dehydrogenase (15-PGDH), a prostaglandin-inhibiting enzyme, and enhances tissue regeneration in various tissue types. TRD is in the preclinical stage of development and the efficacies of each of its indications are being explored in vitro and in vivo by Dr. Markowitz and his team of researchers at CWRU. The purpose of this thesis is to analyze TRD's potential to enhance the standard of care and to navigate the commercial and regulatory landscapes over a variety ofpotential indications. 2014-08-29 English text Case Western Reserve University School of Graduate Studies / OhioLINK http://rave.ohiolink.edu/etdc/view?acc_num=case1402249985 http://rave.ohiolink.edu/etdc/view?acc_num=case1402249985 unrestricted This thesis or dissertation is protected by copyright: all rights reserved. It may not be copied or redistributed beyond the terms of applicable copyright laws. |
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language |
English |
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topic |
Biology Bone Marrow Transplant STEP Liver Resection Ulcerative Colitis PGDH PGDH-15 Prostaglandins Stem Cells Regenerative Medicine |
spellingShingle |
Biology Bone Marrow Transplant STEP Liver Resection Ulcerative Colitis PGDH PGDH-15 Prostaglandins Stem Cells Regenerative Medicine Webber, Nicholas R. Technology and Commercial Assessment of a Tissue Regenerating Drug in the Regenerative Medicine Market |
author |
Webber, Nicholas R. |
author_facet |
Webber, Nicholas R. |
author_sort |
Webber, Nicholas R. |
title |
Technology and Commercial Assessment of a Tissue Regenerating Drug in the Regenerative Medicine Market |
title_short |
Technology and Commercial Assessment of a Tissue Regenerating Drug in the Regenerative Medicine Market |
title_full |
Technology and Commercial Assessment of a Tissue Regenerating Drug in the Regenerative Medicine Market |
title_fullStr |
Technology and Commercial Assessment of a Tissue Regenerating Drug in the Regenerative Medicine Market |
title_full_unstemmed |
Technology and Commercial Assessment of a Tissue Regenerating Drug in the Regenerative Medicine Market |
title_sort |
technology and commercial assessment of a tissue regenerating drug in the regenerative medicine market |
publisher |
Case Western Reserve University School of Graduate Studies / OhioLINK |
publishDate |
2014 |
url |
http://rave.ohiolink.edu/etdc/view?acc_num=case1402249985 |
work_keys_str_mv |
AT webbernicholasr technologyandcommercialassessmentofatissueregeneratingdrugintheregenerativemedicinemarket |
_version_ |
1719436291280470016 |