Improve the Diagnosis on Fundus Photography with Deep Transfer Learning
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Case Western Reserve University School of Graduate Studies / OhioLINK
2021
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ndltd-OhioLink-oai-etd.ohiolink.edu-case16216747816557852021-12-01T05:17:24Z Improve the Diagnosis on Fundus Photography with Deep Transfer Learning Guo, Chen Artificial Intelligence Computer Science Bioinformatics fundus photography deep Learning transfer learning visualization Fundus photography-based eye disease prediction attracted great attention since breakthroughs in deep convolutional neuron networks (DCNNs). However, the performance of existing studies focusing on identifying the right disease among several candidates,which is close to clinical diagnosis in practice,is at most mediocre. Moreover, obtaining large labeled dataset is difficult due to privacy concerns, resulting in the infeasibility to train huge DCNNs. Hence, we propose to utilize a lightweight deep learning architecture (MobileNetV2) and transfer learning to distinguish four eye diseases from normal controls using a small dataset. A visualization approach is also applied to highlight the loci for the predicted label, which may give some hints for further fundus image studies. Our experimental results show that our system achieves an average accuracy of 96.2%, sensitivity of 90.4%, and specificity of 97.6% via five independent runs, and outperforms two other deep learning based algorithms both in accuracy and efficiency. 2021-06-21 English text Case Western Reserve University School of Graduate Studies / OhioLINK http://rave.ohiolink.edu/etdc/view?acc_num=case1621674781655785 http://rave.ohiolink.edu/etdc/view?acc_num=case1621674781655785 unrestricted This thesis or dissertation is protected by copyright: some rights reserved. It is licensed for use under a Creative Commons license. Specific terms and permissions are available from this document's record in the OhioLINK ETD Center. |
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English |
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Artificial Intelligence Computer Science Bioinformatics fundus photography deep Learning transfer learning visualization |
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Artificial Intelligence Computer Science Bioinformatics fundus photography deep Learning transfer learning visualization Guo, Chen Improve the Diagnosis on Fundus Photography with Deep Transfer Learning |
author |
Guo, Chen |
author_facet |
Guo, Chen |
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Guo, Chen |
title |
Improve the Diagnosis on Fundus Photography with Deep Transfer Learning |
title_short |
Improve the Diagnosis on Fundus Photography with Deep Transfer Learning |
title_full |
Improve the Diagnosis on Fundus Photography with Deep Transfer Learning |
title_fullStr |
Improve the Diagnosis on Fundus Photography with Deep Transfer Learning |
title_full_unstemmed |
Improve the Diagnosis on Fundus Photography with Deep Transfer Learning |
title_sort |
improve the diagnosis on fundus photography with deep transfer learning |
publisher |
Case Western Reserve University School of Graduate Studies / OhioLINK |
publishDate |
2021 |
url |
http://rave.ohiolink.edu/etdc/view?acc_num=case1621674781655785 |
work_keys_str_mv |
AT guochen improvethediagnosisonfundusphotographywithdeeptransferlearning |
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1723963320495505408 |