Determination of Urinary 2-Naphthol Concentration in Rubber Manufacturing Workers

Determination of Urinary 2-Naphthol Concentration in Rubber Manufacturing Workers

Bibliographic Details
Main Author: Gaultney, Beverly Teal
Language:English
Published: University of Cincinnati / OhioLINK 2010
Subjects:
Occupational Safety
2-naphthol
urinary biomarkers
PAH monitoring
rubber workers
naphthalene
urinary naphthols
Online Access:http://rave.ohiolink.edu/etdc/view?acc_num=ucin1266608357
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spelling ndltd-OhioLink-oai-etd.ohiolink.edu-ucin12666083572021-08-03T06:13:52Z Determination of Urinary 2-Naphthol Concentration in Rubber Manufacturing Workers Gaultney, Beverly Teal Occupational Safety 2-naphthol urinary biomarkers PAH monitoring rubber workers naphthalene urinary naphthols Polycyclic aromatic hydrocarbons (PAHs), which consist of 2 or more fused benzene rings, are formed by the incomplete combustion of fossil fuels. Although PAHs are an exposure concern in many industrial sectors, one industry of particular interest is the rubber industry. PAHs make up around 20% of the total weight of rubber products including tires. For tire manufacturing, PAH exposures arise when they are added as extender oils and they may also be present when carbon black is used to produce the master batch material (IARC, 1982). Such exposures have been of public health interest because epidemiology studies of workers exposed to PAHs have identified an increase risk of developing cancers of the lungs, urinary bladder, skin, and prostate (Bofetta et al 1997; Constantino et al 1995). Naphthalene is the simplest and most volatile member of the PAHs. The major route of elimination of naphthalene is via the formation of the hydroxylated metabolites 1- and 2- naphthol which are excreted through the urine (Onyemauwa et al 2009; Serdar et al 2004; Preuss et al 2003). The hypothesis of this thesis is that Post-shift urinary 2-naphthol levels are significantly higher than pre-shift urinary 2-naphthol levels in rubber workers exposed to naphthalene. 2010-04-12 English text University of Cincinnati / OhioLINK http://rave.ohiolink.edu/etdc/view?acc_num=ucin1266608357 http://rave.ohiolink.edu/etdc/view?acc_num=ucin1266608357 unrestricted This thesis or dissertation is protected by copyright: some rights reserved. It is licensed for use under a Creative Commons license. Specific terms and permissions are available from this document's record in the OhioLINK ETD Center.
collection NDLTD
language English
sources NDLTD
topic Occupational Safety
2-naphthol
urinary biomarkers
PAH monitoring
rubber workers
naphthalene
urinary naphthols
spellingShingle Occupational Safety
2-naphthol
urinary biomarkers
PAH monitoring
rubber workers
naphthalene
urinary naphthols
Gaultney, Beverly Teal
Determination of Urinary 2-Naphthol Concentration in Rubber Manufacturing Workers
author Gaultney, Beverly Teal
author_facet Gaultney, Beverly Teal
author_sort Gaultney, Beverly Teal
title Determination of Urinary 2-Naphthol Concentration in Rubber Manufacturing Workers
title_short Determination of Urinary 2-Naphthol Concentration in Rubber Manufacturing Workers
title_full Determination of Urinary 2-Naphthol Concentration in Rubber Manufacturing Workers
title_fullStr Determination of Urinary 2-Naphthol Concentration in Rubber Manufacturing Workers
title_full_unstemmed Determination of Urinary 2-Naphthol Concentration in Rubber Manufacturing Workers
title_sort determination of urinary 2-naphthol concentration in rubber manufacturing workers
publisher University of Cincinnati / OhioLINK
publishDate 2010
url http://rave.ohiolink.edu/etdc/view?acc_num=ucin1266608357
work_keys_str_mv AT gaultneybeverlyteal determinationofurinary2naphtholconcentrationinrubbermanufacturingworkers
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