Overexpression of the human optic atrophy-associated OPA1 gene induces mitochondrial and cellular fitness defects in yeast

Overexpression of the human optic atrophy-associated OPA1 gene induces mitochondrial and cellular fitness defects in yeast

Bibliographic Details
Main Author:	Almazan, Annabel Vivian P.
Language:	English
Published:	Wright State University / OhioLINK 2020
Subjects:	Biology Molecular Biology Genetics OPA1 mitochondria mitochondrial dynamics mitochondrial fusion mitochondrial fission dominant optic atrophy optic atrophy type 1 gene
Online Access:	http://rave.ohiolink.edu/etdc/view?acc_num=wright1590861295140841

Similar Items

Dominant Optic Atrophy (DOA): Modeling the Kaleidoscopic Roles of OPA1 in Mitochondrial Homeostasis
by: Valentina Del Dotto, et al.
Published: (2021-06-01)

OPA1 et atrophie optique dominante : étude physiopathologique par approche métabolomique et lipidomique
by: Bocca, Cinzia isabelle
Published: (2018)

Not only dominant, not only optic atrophy: expanding the clinical spectrum associated with OPA1 mutations
by: Alessia Nasca, et al.
Published: (2017-05-01)

A novel AFG3L2 mutation close to AAA domain leads to aberrant OMA1 and OPA1 processing in a family with optic atrophy
by: Valentina Baderna, et al.
Published: (2020-06-01)

OPA1-Exon4b Binds to mtDNA D-Loop for Transcriptional and Metabolic Modulation, Independent of Mitochondrial Fusion
by: Liang Yang, et al.
Published: (2020-04-01)

Parkin Overexpression Attenuates Sepsis-Induced Muscle Wasting
by: Jean-Philippe Leduc-Gaudet, et al.
Published: (2020-06-01)

Homozygous YME1L1 mutation causes mitochondriopathy with optic atrophy and mitochondrial network fragmentation
by: Bianca Hartmann, et al.
Published: (2016-08-01)

Mitochondrial fusion/fission dynamics in neurodegeneration and neuronal plasticity
by: A.M. Bertholet, et al.
Published: (2016-06-01)

Two novel compound heterozygous mutations in OPA3 in two siblings with OPA3-related 3-methylglutaconic aciduria
by: Christina Lam, et al.
Published: (2014-01-01)

Dominant optic atrophy in Denmark – report of 15 novel mutations in <it>OPA1</it>, using a strategy with a detection rate of 90%
by: Almind Gitte J, et al.
Published: (2012-08-01)

Analyse bio-informatique du protéome mitochondrial et du spectre des mutations de la protéine Opa1
by: Ferré, Marc
Published: (2009)

Optimized OPA1 Isoforms 1 and 7 Provide Therapeutic Benefit in Models of Mitochondrial Dysfunction
by: Daniel M. Maloney, et al.
Published: (2020-11-01)

Medical management of hereditary optic neuropathies
by: Chiara eLa Morgia, et al.
Published: (2014-07-01)

Molecular Mechanisms behind Inherited Neurodegeneration of the Optic Nerve
by: Alessandra Maresca, et al.
Published: (2021-03-01)

OPA1-related disorders: Diversity of clinical expression, modes of inheritance and pathophysiology
by: Juan Manuel Chao de la Barca, et al.
Published: (2016-06-01)

A Perspective on Accelerated Aging Caused by the Genetic Deficiency of the Metabolic Protein, OPA1
by: Irina Erchova, et al.
Published: (2021-04-01)

OPA1: 516 unique variants and 831 patients registered in an updated centralized Variome database
by: Bastien Le Roux, et al.
Published: (2019-09-01)

Mitochondrial Membrane Dynamics—Functional Positioning of OPA1
by: Hakjoo Lee, et al.
Published: (2018-12-01)

Exercise, mitochondrial biogenesis and disuse-induced atrophy
by: Şenay Akın, et al.
Published: (2021-06-01)

Repeated Aconitine Treatment Induced the Remodeling of Mitochondrial Function via AMPK–OPA1–ATP5A1 Pathway
by: Li-Zhen Qiu, et al.
Published: (2021-06-01)

Dominant mutations in MIEF1 affect mitochondrial dynamics and cause a singular late onset optic neuropathy
by: Majida Charif, et al.
Published: (2021-02-01)

Opa1 Reduces Hypoxia-Induced Cardiomyocyte Death by Improving Mitochondrial Quality Control
by: Ting Xin, et al.
Published: (2020-08-01)

First submicroscopic inversion of the OPA1 gene identified in dominant optic atrophy – a case report
by: Nicole Weisschuh, et al.
Published: (2020-11-01)

Mitochondrial Fusion Via OPA1 and MFN1 Supports Liver Tumor Cell Metabolism and Growth
by: Meng Li, et al.
Published: (2020-01-01)

A yeast-based screening assay identifies repurposed drugs that suppress mitochondrial fusion and mtDNA maintenance defects
by: Thomas Delerue, et al.
Published: (2019-02-01)

Mitochondrial Mutations in Ethambutol-Induced Optic Neuropathy
by: Xiao-Hui Zhang, et al.
Published: (2021-10-01)

Concurrent OPA1 mutation and chromosome 3q deletion leading to Behr syndrome: a case report
by: Ting Zeng, et al.
Published: (2020-09-01)

The Role of OPA1 and Interacting Proteins in Mitochondrial Function
by: Patten, David A
Published: (2015)

Opa1 Deficiency Promotes Development of Retinal Vascular Lesions in Diabetic Retinopathy
by: Dongjoon Kim, et al.
Published: (2021-05-01)

Fusion Mitochondriale et Effets Vasculaires : rôle de OPA 1 dans l'hypertension artérielle et le vieillissement
by: Nguyen, Phuc Minh Chau
Published: (2015)

Genome-wide RNAi Screen Identifies Romo1 as a Novel Regulator of Mitochondrial Fusion and Cristae Integrity
by: Norton, Matthew
Published: (2013)

The Maintenance of Mitochondrial DNA Integrity and Dynamics by Mitochondrial Membranes
by: James Chapman, et al.
Published: (2020-08-01)

Pleiotropic effects of mdivi-1 in altering mitochondrial dynamics, respiration, and autophagy in cardiomyocytes
by: Richa Aishwarya, et al.
Published: (2020-09-01)

Exercise Pretreatment Promotes Mitochondrial Dynamic Protein OPA1 Expression after Cerebral Ischemia in Rats
by: Li Zhang, et al.
Published: (2014-03-01)

Ocular manifestations of mitochondrial disease
by: S. D. Mathebula
Published: (2012-12-01)

Novel OPA1 mutation featuring spastic paraparesis and intestinal dysmotility
by: Mohamed Kazamel, et al.
Published: (2014-01-01)

Novel role of the SIRT4-OPA1 axis in mitochondrial quality control
by: Alexander Lang, et al.
Published: (2017-12-01)

Cell cycle-dependent association of plectin 1b regulates mitochondrial morphology and function
by: Aebig, Trudy J.
Published: (2011)

Cold Treatment Induces Transient Mitochondrial Fragmentation in Arabidopsis thaliana in a Way that Requires DRP3A but not ELM1 or an ELM1-Like Homologue, ELM2
by: Shin-ichi Arimura, et al.
Published: (2017-10-01)

Results of Mitochondrial DNA Sequence Analysis in Patients with Clinically Diagnosed Leber’s Hereditary Optic Neuropathy
by: Haluk Esgin, et al.
Published: (2012-09-01)