Delineating epigenetic regulatory mechanisms of cell profileration and differentiation
Recent advances in high throughput technology have opened the door to systematic studies of epigenetic mechanisms. One of the key components in the regulation of the cell cycle and differentiation is the retinoblastoma protein (pRB), a component of the RB/E2F tumor suppressor pathway that is frequen...
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Format: | Doctoral Thesis |
Language: | English |
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Universitat Pompeu Fabra
2012
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Online Access: | http://hdl.handle.net/10803/85721 |