Synaptic Plasticity in Basal Ganglia Output Neurons in Parkinson's Disease Patients
Parkinson’s disease (PD) is characterized by the loss of dopamine in the basal ganglia and leads to paucity of movements, rigidity of the limbs, and rest tremor. Synaptic plasticity was characterized in the substantia nigra pars reticulata (SNr), a basal ganglia output structure, in 18 PD patients u...
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Language: | en_ca |
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2009
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Online Access: | http://hdl.handle.net/1807/18986 |