The Role of Gli3 Transcription Factor in the Developing Mouse Stomach
The Sonic hedgehog (Shh) signaling pathway plays a critical role in murine gastric development. When Shh is knocked out in the mouse embryonic stomach, glandular epithelial hyperplasia occurs. Furthermore, this phenotype was mimicked in Gli3−/−, but not Gli2−/− stomachs. I utilized three additional...
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| Language: | en_ca |
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2012
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| Online Access: | http://hdl.handle.net/1807/32234 |