Distal Enhancer – Gene Interactions at the Lmo2 locus in Mouse Erythroid cells
Distal regulatory elements (DREs) have been identified upstream of the hematopoietic regulator Lim domain only 2 (Lmo2) gene in the human and mouse genomes. In this thesis I have investigated how these elements regulate Lmo2 transcription in erythroid cells. My results show that strong chromatin-ch...
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| Language: | en_ca |
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2012
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| Online Access: | http://hdl.handle.net/1807/33337 |
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