The Effects of CREB-mediated BDNF Expression on Memory- and Anxiety-related Behaviours in the Adult Mouse

Experience drives changes in gene expression that mold and reorganize neuronal circuits. In response to neuronal activity, the transcription factor CREB binds to a regulatory site on Bdnf promoter IV to modulate BDNF protein levels. CREB and BDNF are extensively implicated in animal behaviour, but t...

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Bibliographic Details
Main Author: Florczynski, Matthew
Other Authors: Josselyn, Sheena
Language:en_ca
Published: 2012
Subjects:
Online Access:http://hdl.handle.net/1807/33420

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