Functional Characterization of Amphiphysin in Drosophila melanogaster
Amphiphysin (Amph) is a multi-domain protein that has been implicated in synaptic vesicle (SV) endocytosis. In vertebrates, Amph1 associates with SVs and binds to known endocytic proteins, such as dynamin and clathrin. Overexpression of the vertebrate Amph1 SH3 domain is sufficient to inhibit SV end...
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| Language: | en_ca |
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2012
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| Online Access: | http://hdl.handle.net/1807/33961 |