Role of P-glycoprotein in the Intestinal Absorption of Etoposide in Rats

Role of P-glycoprotein in the Intestinal Absorption of Etoposide in Rats

碩士 === 國立成功大學 === 藥理學研究所 === 81 === P-醣蛋白(P-glycoprotein;Pgp)以主動運輸的方式將許多化學治療劑例如 etoposide 打出癌細胞，導致多重抗藥性(multidrug resistance)。 Pgp不僅存在癌細胞，也存在某些正常組織，例如小腸黏膜刷狀毛(brush border)細胞膜。Quinidine,臨床上是抗心律不整藥，過去證據顯示它能克服多重抗藥性，其作用可能藉由干擾Pg...

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Bibliographic Details
Main Authors:	Bee-Lien Leu, 陸碧蓮
Other Authors:	Jin-ding Huang
Format:	Others
Language:	zh-TW
Published:	1993
Online Access:	http://ndltd.ncl.edu.tw/handle/25560215636876652430

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