| Summary: | 碩士 === 東海大學 === 化學工程研究所 === 82 === The purpose of this thesis is to investigate the adhesion
behavior of a elastic colloid to a flat plate theoretically,
and the results will be applyied to study the adhesion of
white blood cell. The necessary conditions for the white blood
cell adhesion onto the vessel wall will be discussed. With
the Hertz contact theory of linear elasticity, and the
lubrication theory, the relationships of elastic deformation
and pressure force, and that of drag force during the adhesion
period are established. For the interaction force between
colloidal surface and plate surface, the van der Waals force
and the electrostatic force will be considered in the above
model. From the results of numerical simulation, it is found
that the greater the initial kinetic energy of colloidal
particle owned, the smaller the separation distance between
particle and plate surface induced, and the greater tendency
of particle rebounded. Due to the easier storge of elastic
energy, the separation distance will become larger for these
more deformable colloidal particle; i.e. , the white blood
cell. A larger van der Waals force can pull the non-contact
cell more closely to the plate surface. For the experimental
part, the surface characteristics of white blood cell is
investigated, by A F M , it is found that these are some
extrasive parts around the peripheral side of the cell, and
the surface of the cell is not so smooth as expected.
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