Injuries of End-plate and Intervertebral Disc under Cyclic Compression Loading: A correlation between MRI and Anatomic findings

• Main Authors: Horng-Woei Song, 宋宏偉
• Other Authors: G.L. Chang; R.M. Lin; C.Y. Yu
• Format: Others
• Language: zh-TW
• Published: 1996
• Online Access: http://ndltd.ncl.edu.tw/handle/87461725573079552326

碩士 === 國立成功大學 === 醫學工程學系 === 84 === Intervertebral disc problem is one of the most common cause of low back pain. Slowly repetitive loading was considered to be the contributing factor of disc injuries.42 body-disc-body units were prepared from 14 fresh porcine spines. Six units was taken as control group for comparison of MRI and with the experimental group which was the other 36 units subjected to low cyclic compression test. The experimental group was further divided into three groups which were subjected to cyclic compression test at the rate of 10, 20, 30 mm / min repetitively. 300 cycles were applied in every specimen. The observation of morphology was obtained through sagittal and transverse section by using stereomicroscope. The results indicated, the effect of different speed and geometric morphology change of the discs by MRI were irrelevant.The result which different speed versus strength decay of intervertebral disc was found non-significant. This study eliminated speed dimension. The relationships between MRI and anatomic findings were lower correlation. Only nucleus shape and marginal change were more congruous. About disc failure, the discs were sure to change of geometric morphology, such as sagittal section could detect fibers buckling and microcleft. Transverse section had a phenomenon which fibril generated into the nucleus. and bleeding around disc. This result showed that possible cartilage had broken somewhere in spinal end-plate, although there was not generated visually disc herniation. Change of disc early degeneration should produce by slowly repetitive loading. In conclusion, The research of injuries of acute end-plate and intervertebral disc was offered a reference of the correspondence of clinical practicable case through cyclic test.