Development of a uric acid biosensing system for haemodialysis waste monitoring

• Main Authors: Hu,Yi-Wen, 胡以文
• Other Authors: Jan,Gwo-Jen;Hsu,Tien-Tsai
• Format: Others
• Language: zh-TW
• Published: 1996
• Online Access: http://ndltd.ncl.edu.tw/handle/50750350268640075657

碩士 === 國立臺灣大學 === 電機工程研究所 === 84 === Based on an immobilized uricase reactor and a thick-film hydrogen peroxide platinum electrode, a biosensor for uric acid has been developed in this investigation. The uric acid sensor was combined with a flow injection analysis system to structure a bioanalytical system for monitoring the uric acid content in the haemodialysis waste. The effect of interferents in the sample had been reduced by modifying the electrode surface with an electropolymerized 1,3-diaminobenzene / resorcinol film. The resulted system could measure uric acid with a linear range from 0.01 to 0.4 mg/dl and sensitivity 97.4nA/mg/dl. The detection limit was 0.01 mg/dl. The correlation coefficient with the clinical photometric method was 0.97.