Anti-aging Effect of Chinese Medicines Luh-Wey-Dih-Hwang-Tang and Syh-Jiun-Tzyy-Tang in Cultured Human Embryo Lung Diploid Cells

• Main Authors: Tsai, Fuu-Jen, 蔡輔仁
• Other Authors: Chang-Hai Tsai
• Format: Others
• Language: zh-TW
• Published: 1997
• Online Access: http://ndltd.ncl.edu.tw/handle/54073813108345451549

博士 === 中國醫藥學院 === 中國醫學研究所 === 85 === The anti-aging effects of two Chinese medicines were evaluated in cultured human embryo lung diploid cells.In order to search for a possible mechanism of aging, the enzyme activities of superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) were measured in different generations of cultured cells. Paraquat was introduced into some groups of culture cells to generate free radicals and produce cell damage. The enzyme activity of SOD and GSH-Px increased remarkably in the groups treated with Luh-Wey-Dih-Hwang-Tang (六味地黃湯). The life span of cells in this group was significantly prolonged when compared with the control group. The anti-aging effect of Luh-Wey- Dih-Hwang-Tang may come from the activity enhanament of SOD and GSH-Px.The life span was shortened in all groups of culture cells treated with paraquat. The group treated with paraquat and Syh- Jiun-Tzyy-Tang(四君子湯)had longer life span than the other groups treated with paraquat. The anti-aging effect of Syh- Jiun-Tzyy-Tang may via the effect of anti-free-radical and anti- oxidant of Panax ginseng.