Comparison of the Concentration of Lactate, Creatinine, Blood Urea Nitrogen and Uric Acid between Saliva and Blood

• Main Authors: Chin-Chuan Huang, 黃欽詮
• Other Authors: Mei-Chich Hsu
• Format: Others
• Language: zh-TW
• Published: 1999
• Online Access: http://ndltd.ncl.edu.tw/handle/94696043790359626803

碩士 === 國立體育學院 === 運動科學研究所 === 87 === Saliva is used as a biological fluid to replace the blood in some clinical diagnoses. To get the saliva is more convenient and easier than that of blood. The present study is to investigate whether the blood can be substituted by saliva to determine the concentration of lactate, creatinine, blood urea nitrogen and uric acid. Eighteen subjects(10 female, 8 male) participated in the first part of this study. Saliva and blood were collected in the same time at rest. Samples were analyzed by a dry-type blood analyzer, which was the most frequently used blood analyzer in Taiwan sports society. Our results showed the higher correlation values of lactate(r=0.85) and creatinine(r=0.77) between saliva and blood(p<0.05). The correlation values of blood urea nitrogen(r=0.62) and uric acid(r=0.50) between saliva and blood also reached the significant level at α=0.05. Five subjects(3 female, 2 male) participated in the second part of this study. Saliva and blood were collected and analyzed at 5 minute intervals during the performance of a graded exercise test on a cycle ergometer against increasing workloads. The correlation of lactate between saliva and blood was all above 0.94. We suggest that saliva can be used as an alternative fluid to determine the lactate and creatinine.