Synthetic study of marine natural products
碩士 === 國立交通大學 === 應用化學系 === 87 === (I) The total synthesis of 2-isocyanoallopupukeanane, a metabolite secreted by nudibranch mollusks, was accomplished in nineteen steps from cyclopentadiene in ca. 5% overall yield. A highly stereoselective synthesis of this unique compound by sigmatropic...
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ndltd-TW-087NCTU05000352016-07-11T04:13:50Z http://ndltd.ncl.edu.tw/handle/49826572272985237968 Synthetic study of marine natural products 海產天然物合成研究 Liang-Rern Kung 龔亮仁 碩士 國立交通大學 應用化學系 87 (I) The total synthesis of 2-isocyanoallopupukeanane, a metabolite secreted by nudibranch mollusks, was accomplished in nineteen steps from cyclopentadiene in ca. 5% overall yield. A highly stereoselective synthesis of this unique compound by sigmatropic reaction is the subject of our synthetic strategy. (II) Kainic acid, one of the representative agonists of excitatory amino acid receptors, has attracted considerable interest due to its unique structure and neuroexcitatory properties. While the total synthesis of this trisubstituted pyrrolidine ring have already been reported by several research groups, our approach to the kainic acid relied on the Diels-Alder reaction of N-butadienyl amide with methyl acrylate. Tse-Lok Ho 何子樂 1999 學位論文 ; thesis 112 en_US |
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碩士 === 國立交通大學 === 應用化學系 === 87 === (I) The total synthesis of 2-isocyanoallopupukeanane, a metabolite secreted by nudibranch mollusks, was accomplished in nineteen steps from cyclopentadiene in ca. 5% overall yield. A highly stereoselective synthesis of this unique compound by sigmatropic reaction is the subject of our synthetic strategy.
(II) Kainic acid, one of the representative agonists of excitatory amino acid receptors, has attracted considerable interest due to its unique structure and neuroexcitatory properties. While the total synthesis of this trisubstituted pyrrolidine ring have already been reported by several research groups, our approach to the kainic acid relied on the Diels-Alder reaction of N-butadienyl amide with methyl acrylate.
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author2 |
Tse-Lok Ho |
author_facet |
Tse-Lok Ho Liang-Rern Kung 龔亮仁 |
author |
Liang-Rern Kung 龔亮仁 |
spellingShingle |
Liang-Rern Kung 龔亮仁 Synthetic study of marine natural products |
author_sort |
Liang-Rern Kung |
title |
Synthetic study of marine natural products |
title_short |
Synthetic study of marine natural products |
title_full |
Synthetic study of marine natural products |
title_fullStr |
Synthetic study of marine natural products |
title_full_unstemmed |
Synthetic study of marine natural products |
title_sort |
synthetic study of marine natural products |
publishDate |
1999 |
url |
http://ndltd.ncl.edu.tw/handle/49826572272985237968 |
work_keys_str_mv |
AT liangrernkung syntheticstudyofmarinenaturalproducts AT gōngliàngrén syntheticstudyofmarinenaturalproducts AT liangrernkung hǎichǎntiānránwùhéchéngyánjiū AT gōngliàngrén hǎichǎntiānránwùhéchéngyánjiū |
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