| Summary: | 碩士 === 國立交通大學 === 應用化學系 === 88 === Water-Compressed Fluids Partition Coefficient Measurements of Organic Solutes Using Countercurrent Chromatography
Student:Jia-Yaw Chang Advisor:Tiing Yu*
Institute of Applied Chemistry
National Chiao Tung University
Abstract
Extraction of organic substances from aqueous solutions using supercritical fluid carbon dioxide (SF CO2) has drawn attentions. It helps to predict the recovery yields in applications if the partition coefficients are determined in advance. The partition coefficient was usually determined by placing the aqueous sample with SF CO2 in a high-pressure cell. After thorough mixing, the solutions of both phases were sampled in order to measure the solubilities of the organic compound in each phase. The partition coefficient could be calculated accordingly. We utilized a high-pressure countercurrent chromatography (CCC) system to determine the coefficients. Parameters that were used to calculate the coefficient, including the stationary phase-retention volume, the retention volume of the solute, and the dead volume, could be obtained by one chromatographic run. In addition to SF CO2, we also measured water-1,1,1,2-tetrafluoroethane partition coefficients of some organic compounds using commercialized high speed CCC. The partition coefficients of a group of organic compounds could be determined simultaneously when the aqueous sample of a mixture was separated in the CCC column. The experimental data showed very good reproducibility.
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