| Summary: | 碩士 === 國立交通大學 === 應用化學系 === 88 === The method of the headspace solid-phase microextraction (HS-SPME) combining capillary gas chromatography with flame ionization detector (GC-FID) was employed to analyze glycol ether acetates and related compounds. These compounds have highly solvent properties and are miscible with most organic solvent and water. For the characteristics, these compounds have been widely used in dyes, paints, inks and others. Several potential health effect have been reported in animals experimentally exposed to these chemicals, like embryotoxicity, teratogenicity, testicular damage, and hematological effects.
The extraction efficiencies of several SPME fibers were examined. The carboxen-polydimethylsiloxan (CAR-PDMS) fiber was used for subsequent analysis. The factors affecting the headspace SPME procedure, such as extraction temperature, extraction time, salt addition, stirring and sample volume, were discussed via an orthogonal array design. The results show that HS-SPME combining capillary gas chromatography with flame ionization detector is a reproducible method for qualitative and quantitative determination of glycol ether acetates at ppb levels.
|
|---|
