Palladium-Catalyzed Three-Component Coupling Reactions of Allenes,Acid Chlorides,and Organotin Reagents
碩士 === 國立清華大學 === 化學系 === 88 === Acyl chlorides R1COCl, allenes R2R3CCCH2 and organotin reagents Bu3SnR4 undergo three-component coupling reaction in toluene in the presence of Pd(dba)2 to give functionally substituted a, b unsaturated ketones R2R3C=C(COR1)CH2R4. Based on known palladium-allene and...
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| Format: | Others |
| Language: | zh-TW |
| Published: |
2000
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| Online Access: | http://ndltd.ncl.edu.tw/handle/08846020082923449379 |
| Summary: | 碩士 === 國立清華大學 === 化學系 === 88 === Acyl chlorides R1COCl, allenes R2R3CCCH2 and organotin reagents Bu3SnR4 undergo three-component coupling reaction in toluene in the presence of Pd(dba)2 to give functionally substituted a, b unsaturated ketones R2R3C=C(COR1)CH2R4. Based on known palladium-allene and -allyl chemistry, we propose a mechanism to account for this palladium-catalyzed three-component coupling reactions.
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