The Study of Hong-Chyi on Insulin Secretion in Perfused Rat Pancreas

碩士 === 中國醫藥學院 === 中國醫學研究所 === 89 === The Study of Hong-Chyi on Insulin Secretion in Perfused Rat Pancreas Hong-Chyi is one of the most popular Spleen-Fostering, Qi-Supple- menting Chinese herbs used in Taiwan. The purpose of this study is to ev- aluate the ef...

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Bibliographic Details
Main Author: 林齊魁
Other Authors: 蘇奕彰
Format: Others
Language:zh-TW
Published: 2001
Online Access:http://ndltd.ncl.edu.tw/handle/12823820263152464140
Description
Summary:碩士 === 中國醫藥學院 === 中國醫學研究所 === 89 === The Study of Hong-Chyi on Insulin Secretion in Perfused Rat Pancreas Hong-Chyi is one of the most popular Spleen-Fostering, Qi-Supple- menting Chinese herbs used in Taiwan. The purpose of this study is to ev- aluate the effect of Hong-Chyi on insulin secretion in perfused rat pancreas. Four doses (650 mg,390 mg,130 mg,control) of Hong-Chyi crew extract were used. The perfused rat pancreas was adopted with competitive radioimmunoassay to evaluate the change of insulin secretion induced by Hong-Chyi. The statistical analysis was performed using ANOVA. Our result showed the perfusion of Hong-Chyi could stimulate the secretion of insulin, and obtain the obvious peak in dose-dependent response. Once the peak was obtained, the secretion of insulin decreased gradually. The insulin secretion function of islet cells remained intact after perfusion. Key words:Insulin secretion; Spleen-fostering; Qi-Supplementing; Hong-chyi; Radioimmunoassay