Pulmonary Artery Catheter Replacement Association with Infections in the Intensive Care Unit

• Main Authors: Chen Yin Yin, 陳瑛瑛
• Other Authors: Pesus Chou
• Format: Others
• Language: zh-TW
• Published: 2001
• Online Access: http://ndltd.ncl.edu.tw/handle/93660362308614516526

碩士 === 國立陽明大學 === 公共衛生研究所 === 89 === OBJECTIVE: To compare catheter associated infections between different lengths of replacement, 4-day or 7-day, in pulmonary artery (PA) catheterization replacement. DESIGN: A randomized, controlled trial was conducted in 258 patients with PA catheterization in intensive care unit (ICU) during one-year of study period. All patients were randomized into two groups according to length of replacement of PA catheter and pressure monitoring system: four days and seven days. RESULTS: Ninety-eight (73.7%) in 4-day group and 85 (68%) in 7-day group were enrolled in this study. The power of the test for the above sample size was 88.2% to detect statistical differences in both infection and colonization rates. Positive PA catheter-tip colonizations were found in 14.2% of all patients, 18.8% in 7-day group and 10.2% in 4-day group (OR, 2; CI95, 0.81-5.2). The incidences of catheter-related bacteremia were 1.1 per 1000 catheter-days in 7-day group and 3.8 per 1000 catheter-days in 4-day group. In 7-day group, the PA catheter-related bacteremia was 2% vs. 3.1% in 4-day group (OR, 0.4; CI95, 0.01-4.17) and the infusate-related infection was 2% vs. 0% in 4-day group. CONCLUSION: No statistically significant difference of the PA catheter associated infections was found between 7-day and 4-day of replacement. The duration of PA catheter exchange could extend to 7-day replacement if there is no evidence of catheter-related infection.