automated extraction of protein to protein interactions from biological literatures

• Main Authors: Po-Han Chou, 周伯翰
• Other Authors: Chung Shyan Liu
• Format: Others
• Language: zh-TW
• Published: 2002
• Online Access: http://ndltd.ncl.edu.tw/handle/48969746056254267551

碩士 === 中原大學 === 資訊工程研究所 === 90 === Motivation: To improve the efficiency of using life science literatures storing in digital databases, we designed software to determine the interactions between proteins, which have been described in the abstracts of life science papers. This program will help the researches in genetics and other life sciences. It is using information extraction techniques and can automatically determine the protein interaction information. Finally, this program outputs protein interaction network graphically to research users. Currently, most protein interactions information was described in life science journals or genomic conferences. However, these data were stored in a format that is convenient for human reading but hard for programmer to implement aided software and difficult to perform query task precisely. Therefore, we take advantage of natural language processing techniques and implement the software that will determine the protein interactions. This information extraction system will help analysis of life literatures and gain protein interaction information automatically. Our program achieves the precision rate in about 82%. And we used the abstracts of yeast papers for program test. These papers for test originally stored in Biomolecular Interaction Network Database (BIND).