| Summary: | 碩士 === 國立成功大學 === 機械工程學系碩博士班 === 90 === With the recent of advance in the biomedical engineering, the research of the bio-heat transfer for human body is increasingly from qualitative analysis to quantitative analysis. Therefore people have to know thoroughly the characteristic and theory of heat transfer for human body. The task of the present project is to perform a numerical simulation for estimating the thermal conductivity, blood perfusion rate and blood velocity of biotissue in vivo using given temperature measurements obtained by Pennes[8] , Trezek and Tewett[24]. The hybrid scheme of the Laplace transform technique and the central difference method in conjunction with the least-squares scheme and temperature measurements inside biotissue is applied to estimate the thermophysical properties of biotissue. Time-dependent terms in the governing differential equation and boundary conditions are removed by using the Laplace transform technique, and then the resulting differential equations are solved by using the central difference technique. Due to the application of Laplace transform technique, the temperature at a specific time can be calculated without step by step computation in the time domain. To date, many numerical methods have been proposed for measuring thermophysical properties of the metal material. However, a few numerical methods were proposed for estimating the functional forms of the thermal conductivity and heat capacity per unit volume with temperature measurements, especially for biotissue in vivo. Moreover, the thermophysical properties of biotissue are of increasingly importance for studying biomedical heat transfer. Thus, the present project is valuable for the development on biomedical heat transfer.
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