LACOP - the method of identification of the LocAl Conformations Of Proteins

碩士 === 國立清華大學 === 生命科學系 === 90 === Due to the rapid growth of 3D protein structures solved in recent years, it becomes increasingly important that we need an efficient, automated tool to search similar local 3D fragments embedded in the 3D conformation of proteins. We designed the method...

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Bibliographic Details
Main Authors: David Chang, 張文忠
Other Authors: 黃鎮剛
Format: Others
Language:zh-TW
Published: 2002
Online Access:http://ndltd.ncl.edu.tw/handle/47792820248938713498
Description
Summary:碩士 === 國立清華大學 === 生命科學系 === 90 === Due to the rapid growth of 3D protein structures solved in recent years, it becomes increasingly important that we need an efficient, automated tool to search similar local 3D fragments embedded in the 3D conformation of proteins. We designed the method of identification of the LocAl Conformations Of Proteins (LACOP) software to detect similar local sub-structure of proteins. Our result compared favorable software with fragment-search methods. There were two advantages in LACOP: First, it saved much time to scan whole PDB database. Second, it could compare motif structure.