Effect of oxidized low density lipoprotein on nitric oxide uptake in vascular smooth muscle cells

Effect of oxidized low density lipoprotein on nitric oxide uptake in vascular smooth muscle cells

碩士 === 國立中正大學 === 化學工程研究所 === 91 === In circulation system, nitric oxide (NO) causes the blood vessel dilation through the decrease of intracellular calcium concentration of vascular smooth muscle cell (VSMC). The impairment of NO release from endothelial cells after treatment with oxidiz...

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Main Authors: shin-shyong huang, 黃信雄
Other Authors: Kuang-tse Huang
Format: Others
Language:zh-TW
Published: 2003
Online Access:http://ndltd.ncl.edu.tw/handle/87553055516989387253
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spelling ndltd-TW-091CCU000630382016-06-24T04:15:32Z http://ndltd.ncl.edu.tw/handle/87553055516989387253 Effect of oxidized low density lipoprotein on nitric oxide uptake in vascular smooth muscle cells 氧化低密度脂蛋白對一氧化氮進入血管平滑肌細胞速率的影響 shin-shyong huang 黃信雄 碩士 國立中正大學 化學工程研究所 91 In circulation system, nitric oxide (NO) causes the blood vessel dilation through the decrease of intracellular calcium concentration of vascular smooth muscle cell (VSMC). The impairment of NO release from endothelial cells after treatment with oxidized low density lipoprotein (oxLDL) has been intensively studied. However, the effect of oxLDL on the NO uptake of VSMC remains unclear. In this study, first, the competition experiment of NO between oxyhemoglobin (oxyHb) and VSMC was developed to calculate the relative rate of NO into VSMC. Second, the effects of low density lipoprotein (LDL) and oxLDL on the NO uptake by VSMC was investigated. The result indicated that hydrogen peroxide was able to increase the NO uptake by VSMC. Kuang-tse Huang 黃光策 2003 學位論文 ; thesis 43 zh-TW
collection NDLTD
language zh-TW
format Others
sources NDLTD
description 碩士 === 國立中正大學 === 化學工程研究所 === 91 === In circulation system, nitric oxide (NO) causes the blood vessel dilation through the decrease of intracellular calcium concentration of vascular smooth muscle cell (VSMC). The impairment of NO release from endothelial cells after treatment with oxidized low density lipoprotein (oxLDL) has been intensively studied. However, the effect of oxLDL on the NO uptake of VSMC remains unclear. In this study, first, the competition experiment of NO between oxyhemoglobin (oxyHb) and VSMC was developed to calculate the relative rate of NO into VSMC. Second, the effects of low density lipoprotein (LDL) and oxLDL on the NO uptake by VSMC was investigated. The result indicated that hydrogen peroxide was able to increase the NO uptake by VSMC.
author2 Kuang-tse Huang
author_facet Kuang-tse Huang
shin-shyong huang
黃信雄
author shin-shyong huang
黃信雄
spellingShingle shin-shyong huang
黃信雄
Effect of oxidized low density lipoprotein on nitric oxide uptake in vascular smooth muscle cells
author_sort shin-shyong huang
title Effect of oxidized low density lipoprotein on nitric oxide uptake in vascular smooth muscle cells
title_short Effect of oxidized low density lipoprotein on nitric oxide uptake in vascular smooth muscle cells
title_full Effect of oxidized low density lipoprotein on nitric oxide uptake in vascular smooth muscle cells
title_fullStr Effect of oxidized low density lipoprotein on nitric oxide uptake in vascular smooth muscle cells
title_full_unstemmed Effect of oxidized low density lipoprotein on nitric oxide uptake in vascular smooth muscle cells
title_sort effect of oxidized low density lipoprotein on nitric oxide uptake in vascular smooth muscle cells
publishDate 2003
url http://ndltd.ncl.edu.tw/handle/87553055516989387253
work_keys_str_mv AT shinshyonghuang effectofoxidizedlowdensitylipoproteinonnitricoxideuptakeinvascularsmoothmusclecells
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AT shinshyonghuang yǎnghuàdīmìdùzhīdànbáiduìyīyǎnghuàdànjìnrùxuèguǎnpínghuájīxìbāosùlǜdeyǐngxiǎng
AT huángxìnxióng yǎnghuàdīmìdùzhīdànbáiduìyīyǎnghuàdànjìnrùxuèguǎnpínghuájīxìbāosùlǜdeyǐngxiǎng
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