Imaging the Dynamic Light Propagation in Biological Tissue by Speckle Contrast
碩士 === 中原大學 === 醫學工程研究所 === 91 === Applications of optical measurement methods for physiological signals have become very popular because of the great progress in optical components and techniques. The interference of scattering coherence light inside biological tissues is the basic working principl...
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| Format: | Others |
| Language: | zh-TW |
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2003
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| Online Access: | http://ndltd.ncl.edu.tw/handle/3f7nh3 |
| Summary: | 碩士 === 中原大學 === 醫學工程研究所 === 91 === Applications of optical measurement methods for physiological signals have become very popular because of the great progress in optical components and techniques. The interference of scattering coherence light inside biological tissues is the basic working principle of many biomedical optics measurements. But sometimes, it causes a restriction of measurement range. A better understanding of the interaction between coherence light and biological tissue will be helpful in developing new measurement techniques or overcome the restrictions. A low coherent interferometer system was used to detect the dynamic migration of photon in biological tissues. This measurement would be helpful in understanding how photons propagate in biological tissues.
The structure of the measurement system is Mach-Zender interferometer. The coherence of a semiconductor laser will be adjusted by controlling its driving current. Light will be injected into a scattering sample close to the edge of front surface. The injected photons will encounter multiple scattering before they are absorbed or escape from the front surfaces. Speckle distribution images will be observed on the front surfaces. Using an another reference beam to make the dynamic light propagation in biological tissue.
The measurement image also will be compared with the result of Monte Carlo simulation. Comparison between measurement and simulation results has to be done repeatedly with modification of mathematical model until the best fit between them is found.
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