Biomechanical Evaluation of the Volume and Location of PMMA bone cement in Vertebroplasty
碩士 === 中原大學 === 醫學工程研究所 === 91 === Osteoporotic vertebral compression fracture is one of the most common diseases that attack the elder population especially in postmenopausal women. Most of these patients received conservative treatment such as medication, bracing and rest, but sometimes in vain. I...
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ndltd-TW-091CYCU55300322018-06-25T06:06:27Z http://ndltd.ncl.edu.tw/handle/dsscsk Biomechanical Evaluation of the Volume and Location of PMMA bone cement in Vertebroplasty 椎體成形術中骨水泥容量及位置之生物力學評估 Zheng-Xing Chen 陳政行 碩士 中原大學 醫學工程研究所 91 Osteoporotic vertebral compression fracture is one of the most common diseases that attack the elder population especially in postmenopausal women. Most of these patients received conservative treatment such as medication, bracing and rest, but sometimes in vain. Instrumentation and fusion surgery can be used in some cases, but most of these patients are older and with higher operative risk that are not eligible for these operations. Vertebroplasty involves inserting bone cement (PMMA) into the center of the collapsed spinal vertebra in order to stabilize and strengthen the crushed bone. The two objectives of this study are, (1) to develop a set of instruments used for vertebroplasty with disposable parts (trocar, needle, and syringe), and reusable part (introducer) and to reduce the expense for vertebroplasty, (2) to use a validated finite element model to evaluate the effects of bone cement with different volumes and locations in vertebroplasty and the stress distribution of the vertebral bodies after vertebroplasty. According to our analysis, there is no significant difference between 6-ml, one-sided and 10-ml, two-sided models. The effect of 6-ml, one-sided model was similar to 6-ml, two-sided and even better, but no significant difference. On the biomechanical viewpoint, vertebroplasty is an effective method in increasing biomechanical strength of vertebral bodies. The effects were related to the volumes of bone cement, but not totally proportional to them. There were similar results between the same volumes but different distributions (one-sided, two-sided). One-sided approach seems to be a safer method. We established another model with five motion segments to evaluate the effect of vertebroplasty on the adjacent vertebrae. The result showed that there was no significant effect on the adjacent vertebrae if the height of the injured vertebral body was recovered to the initial height. The introducer we designed is easy-to-use, less expensive and we can effectively control the amount of PMMA to be injected. Wen-Pin Chen Cong-Ren Huang 陳文斌 黃聰仁 2003 學位論文 ; thesis 94 zh-TW |
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碩士 === 中原大學 === 醫學工程研究所 === 91 === Osteoporotic vertebral compression fracture is one of the most common diseases that attack the elder population especially in postmenopausal women. Most of these patients received conservative treatment such as medication, bracing and rest, but sometimes in vain. Instrumentation and fusion surgery can be used in some cases, but most of these patients are older and with higher operative risk that are not eligible for these operations. Vertebroplasty involves inserting bone cement (PMMA) into the center of the collapsed spinal vertebra in order to stabilize and strengthen the crushed bone. The two objectives of this study are, (1) to develop a set of instruments used for vertebroplasty with disposable parts (trocar, needle, and syringe), and reusable part (introducer) and to reduce the expense for vertebroplasty, (2) to use a validated finite element model to evaluate the effects of bone cement with different volumes and locations in vertebroplasty and the stress distribution of the vertebral bodies after vertebroplasty. According to our analysis, there is no significant difference between 6-ml, one-sided and 10-ml, two-sided models. The effect of 6-ml, one-sided model was similar to 6-ml, two-sided and even better, but no significant difference. On the biomechanical viewpoint, vertebroplasty is an effective method in increasing biomechanical strength of vertebral bodies. The effects were related to the volumes of bone cement, but not totally proportional to them. There were similar results between the same volumes but different distributions (one-sided, two-sided). One-sided approach seems to be a safer method. We established another model with five motion segments to evaluate the effect of vertebroplasty on the adjacent vertebrae. The result showed that there was no significant effect on the adjacent vertebrae if the height of the injured vertebral body was recovered to the initial height. The introducer we designed is easy-to-use, less expensive and we can effectively control the amount of PMMA to be injected.
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author2 |
Wen-Pin Chen |
author_facet |
Wen-Pin Chen Zheng-Xing Chen 陳政行 |
author |
Zheng-Xing Chen 陳政行 |
spellingShingle |
Zheng-Xing Chen 陳政行 Biomechanical Evaluation of the Volume and Location of PMMA bone cement in Vertebroplasty |
author_sort |
Zheng-Xing Chen |
title |
Biomechanical Evaluation of the Volume and Location of PMMA bone cement in Vertebroplasty |
title_short |
Biomechanical Evaluation of the Volume and Location of PMMA bone cement in Vertebroplasty |
title_full |
Biomechanical Evaluation of the Volume and Location of PMMA bone cement in Vertebroplasty |
title_fullStr |
Biomechanical Evaluation of the Volume and Location of PMMA bone cement in Vertebroplasty |
title_full_unstemmed |
Biomechanical Evaluation of the Volume and Location of PMMA bone cement in Vertebroplasty |
title_sort |
biomechanical evaluation of the volume and location of pmma bone cement in vertebroplasty |
publishDate |
2003 |
url |
http://ndltd.ncl.edu.tw/handle/dsscsk |
work_keys_str_mv |
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