| Summary: | 碩士 === 高雄醫學大學 === 口腔衛生科學研究所碩士在職專班 === 91 === Abstract
This study aims to discuss the differences among the oral mucosal diseases respectively resulting from pure betel quid chewing, mixed use of betel quid and alcohol, mixed use of betel quid and cigarettes and mixed use of betel quid, cigarettes, and alcohol. 108 sufferers, whose oral mucosal diseases were diagnosed positive by the stomatological doctors in the dental out-patient department, public health office of Mutan county, were obtained as the main subjects in this study. Subsequently, according to the sufferers’ sex, age and their habits of betel quid chewing, 89 local habitants who were diagnosed as non-sufferers of oral mucosal diseases by dentists merely by sight, were selected as the paired group to match with the sufferers by means of questionnaires, which were later entered in the computer through MSAccess, and then statistical analysis was carried out with the statistic software JMP and SAS after all data were filed.
It was found in this study that the association between oral mucosal diseases and betel chewing , smoking and drinking ,and oral submucous fibrosis (OSF) account for the highest percentage, followed by hyperparakeratosis , epithelial hyperplasia or hyperorthokeratosis which may vary in sequence. A betel quid chewer has higher probability of getting OSF and acanthosis than a smoker and a drinker; a smoker has higher probability of getting hyperorthokeratosis than a betel quid chewer and a drinker, especially those smoking more than 2 packets of cigarettes per day have an even higher probability; drinking shows no statistical significance to the types of oral mucosal lesions. In terms of the diverse combination of betel quid chewing, smoking and drinking, age shows no statistical significance to the quantity of betel quid chewed. Hence, it is known that the mere use of betel quid without smoking and drinking will not diminish the likelihood of contracting oral mucosal diseases, contrarily it contributes to even greater chance of getting more types of oral mucosal disease and other coexistent diseases.
In the studies to compare the oral mucosal lesions and the paired group, the oral mucosal lesions group had a lower education level. The betel quid chewing percentage，quantity of betel quid chewed every day，and the number of years that betel quid is chewed were higher in the OSF group than the paired group. A conditional logistic regression model was adopted to analyze the risk factors of all these lesions，a pure betel quid chewer has 4.31-fold probability of contracting oral mucosal diseases while a mixed user of betel quid and cigarettes has 4.86-fold probability, and a chewer of up to 30 betel quid a day has a 2.56-fold probability. They all show a significant difference. By means of post analysis, a mixed user of betel quid and cigarettes has a 1.13-fold probability of getting oral mucosal diseases.
Key words：pure betel quid chewer，mixed betel quid and alcohol，mixed betel quid and smokes，mixed betel quid、smokes and alcohol ，oral mucosal disease.
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