Detection of Biomagnetic Source by the Method of Maximum Entropy

碩士 === 國立中興大學 === 物理學系 === 91 === This thesis applied a novel approach to the detection of active sources in the cortex from magnetic field measurements on the scalp in magnetoencephalograph (MEG). In order to get the neurons’s activation, we have to solve an ill-posed inverse...

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Bibliographic Details
Main Authors: Hong-Yi Bai, 白宏益
Other Authors: H.C. Lee
Format: Others
Language:en_US
Published: 2003
Online Access:http://ndltd.ncl.edu.tw/handle/42333064575228684044
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Summary:碩士 === 國立中興大學 === 物理學系 === 91 === This thesis applied a novel approach to the detection of active sources in the cortex from magnetic field measurements on the scalp in magnetoencephalograph (MEG). In order to get the neurons’s activation, we have to solve an ill-posed inverse problem. Our approach to the solution is the framework of Maximum Entropy on the Mean. A reference probability measure on the random variables is our means of regularizing of the singular nature of the problem. The variables are the intensity of current sources on the cortical region which include all available prior information that help in the regularization. We also introduce a hidden Markov random variable as part of the prior information. The Maximum Entropy method is used again within this framework. Finally, we demonstrate how the method is applied in a practical detection of cerebral activity by analyzing simulated MEG data.