The crystal structure of yeast cytosine deaminase and its application in enzyme-prodrug gene therapy.

碩士 === 國立陽明大學 === 生物藥學研究所 === 91 === Cytosine deaminase (CD, EC 3.5.4.1) catalyzes the deamination of cytosine to uracil and 5-methylcytosine to thymine. The enzyme has been found in bacteria and fungi, where it plays an important role in pyrimidine salvage. However, it is not present in mammalian c...

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Bibliographic Details
Main Authors: Yi-Hsin Hsu, 許憶馨
Other Authors: Jing-Jer Lin
Format: Others
Language:zh-TW
Published: 2003
Online Access:http://ndltd.ncl.edu.tw/handle/76101194356574039295