Anti-allergic effect of milk fermented with lactic acid bacteria
碩士 === 國立中興大學 === 食品科學系 === 92 === The purpose of this investigation was to assess the anti-allergic effect of fermented milk of Streptococcus thermophilus MC, Lactobacillus acidophilus B, Lactobacillus bulgaricus Lb, Lactobacillus bulgaricus 448, and Bifidobacterium longum B6. Female BALB/c mice we...
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ndltd-TW-092NCHU02530462016-06-17T04:16:21Z http://ndltd.ncl.edu.tw/handle/21497158728372527484 Anti-allergic effect of milk fermented with lactic acid bacteria 乳酸菌發酵乳對降低過敏反應之影響 Peng Hsuan Ti 彭瑄第 碩士 國立中興大學 食品科學系 92 The purpose of this investigation was to assess the anti-allergic effect of fermented milk of Streptococcus thermophilus MC, Lactobacillus acidophilus B, Lactobacillus bulgaricus Lb, Lactobacillus bulgaricus 448, and Bifidobacterium longum B6. Female BALB/c mice were immunized intraperitoneally with ovalbumin/complete Freund’s adjuvant to evaluate the specific immune response of mice fed with fermented milk by judging from cytokine, antibody and nitric oxide analysis. Both cultures of spontaneous and OVA-stimulated splenocytes from mice fed with L. bulgaricus Lb of fermented milk expressed significant reduction of IL-4 and promotion of IFN-γ secretion as compared with milk-fed controls. The IL-4 of spontaneous secretion of splenocytes from mice fed with milk fermented with S. thermophilus MC or L. acidophilus B was significantly decreased. When mice fed milk fermented with L. acidophilus B, L. bulgaricusm 448 or B. longum B6, the secretion of IL-6 from cultures of spontaneous or LPS-stimulated peritoneal cells significantly decreased. All tested LAB decreased the secretion of TNF- of LPS-stimulated peritoneal cells from OVA/CFA-primed mice (P < 0.05) and demonstrated the effect of anti-inflammation. The milk fermented with S. thermophilus MC was able to significantly stimulate the secretion of NO from peritoneal cell of mice by activating macrophage. The ratio of IFN-γ to IL-4 of spontaneous secretion of splenocytes, milk fermented with L. bulgaricus Lb significantly increased. The result of anti-OVA-IgE antibody from serum of OVA/CFA-primed mice indicated that S. thermophilus MC is more anti-allergic than that of milk fermented with other tested strains. Meei-Yn Lin, Ph. D. 林美吟 2004 學位論文 ; thesis 73 zh-TW |
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碩士 === 國立中興大學 === 食品科學系 === 92 === The purpose of this investigation was to assess the anti-allergic effect of fermented milk of Streptococcus thermophilus MC, Lactobacillus acidophilus B, Lactobacillus bulgaricus Lb, Lactobacillus bulgaricus 448, and Bifidobacterium longum B6. Female BALB/c mice were immunized intraperitoneally with ovalbumin/complete Freund’s adjuvant to evaluate the specific immune response of mice fed with fermented milk by judging from cytokine, antibody and nitric oxide analysis. Both cultures of spontaneous and OVA-stimulated splenocytes from mice fed with L. bulgaricus Lb of fermented milk expressed significant reduction of IL-4 and promotion of IFN-γ secretion as compared with milk-fed controls. The IL-4 of spontaneous secretion of splenocytes from mice fed with milk fermented with S. thermophilus MC or L. acidophilus B was significantly decreased. When mice fed milk fermented with L. acidophilus B, L. bulgaricusm 448 or B. longum B6, the secretion of IL-6 from cultures of spontaneous or LPS-stimulated peritoneal cells significantly decreased. All tested LAB decreased the secretion of TNF- of LPS-stimulated peritoneal cells from OVA/CFA-primed mice (P < 0.05) and demonstrated the effect of anti-inflammation. The milk fermented with S. thermophilus MC was able to significantly stimulate the secretion of NO from peritoneal cell of mice by activating macrophage. The ratio of IFN-γ to IL-4 of spontaneous secretion of splenocytes, milk fermented with L. bulgaricus Lb significantly increased. The result of anti-OVA-IgE antibody from serum of OVA/CFA-primed mice indicated that S. thermophilus MC is more anti-allergic than that of milk fermented with other tested strains.
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author2 |
Meei-Yn Lin, Ph. D. |
author_facet |
Meei-Yn Lin, Ph. D. Peng Hsuan Ti 彭瑄第 |
author |
Peng Hsuan Ti 彭瑄第 |
spellingShingle |
Peng Hsuan Ti 彭瑄第 Anti-allergic effect of milk fermented with lactic acid bacteria |
author_sort |
Peng Hsuan Ti |
title |
Anti-allergic effect of milk fermented with lactic acid bacteria |
title_short |
Anti-allergic effect of milk fermented with lactic acid bacteria |
title_full |
Anti-allergic effect of milk fermented with lactic acid bacteria |
title_fullStr |
Anti-allergic effect of milk fermented with lactic acid bacteria |
title_full_unstemmed |
Anti-allergic effect of milk fermented with lactic acid bacteria |
title_sort |
anti-allergic effect of milk fermented with lactic acid bacteria |
publishDate |
2004 |
url |
http://ndltd.ncl.edu.tw/handle/21497158728372527484 |
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